Abstarct: The Acid Mine Drainage (AMD), a by-product of mining industry is one of the current most important environmental issues. Acid mine drainage is a drainage with a high acidity (low pH), and high concentration of sulfate which cause the solubility and migration of heavy mextals in toxic waste soils. Acid drainage produces by oxidation of sulfidic minerals which reacts with oxygen and water when it exposure to the air during or after mining activities. In this project, we tested the potential of production and neutralization of acid drainage in mining wastes by static tests. We used Standard Acid-baxse Account, Modified Acid-baxse Account, and Net Acid Generation for mextal Sulfidic waste of concentration factory of Sungun Copper Mine in Tabriz- East Azarbaijan and Coal Sulfidic waste of coal-washing factory of Eastern Alborz Coal-mine in Shahroud-Semnan. The Static tests is used to identify the neutralization potential of Boxite Red-mud waste at Alumina refinery factory in Jajarm-North Khorasan. Also we used batch leaching tests to estimate the potential and magnitude of Boxite Red-mud waste combining with the sulfidic wastes for stabilization and preventing the production of acid mine drainage. For component characterization of samples, X-ray diffraction and X-ray fluorescence analysis were performed to identify mineralogy information and main oxides of waste soils and then the quantities of main and minor elements had been determined by acid extraction test. The geochemical characteristics tests (static tests) results for Coal Sulfidic and mextal Sulfidic waste respectively shows 2.45 and 2.79 for number of net acid generation pH, 552.23 and 50.56 (kgH2SO4/tonne) for net acid generation, 818.75 and 89.71 (kgCaCO3/tonne) for potential of net acid production, and 0.122 and 0.216 for neutralization potential rate. The results interpretation: sulfidic mextals waste is classified as containing "acid production potential with low capacity" and sulfidic coal waste as containing "acid production potential with high capacity". In our Serial Batch Leaching Tests, from the leaching of Boxite Red Mud with synthesized acid drainage extracted from Coal Sulfidic and mextal Sulfidic wastes, the resulted liquid-to-solid ratio is 1/60 and 1/40 respectively, and in a Mixed Batch Leaching Test, from Coal Sulfidic and mextal Sulfidic wastes combined with Boxit Red-mud waste, the … precentage is 10% and 3% respectively, as result we have near neutral pH, low concentration of SO4 and low acidity…. resulted liquid-to-solid ratio is 1/60 and 1/40 respectively, and in a Mixed Batch Leaching Test, from Coal Sulfidic and mextal Sulfidic wastes respectively, and in a Mixed Batch Leaching Test, from Coal Sulfidic and mextal Sulfidic wastes.