Abstarct: Waste water of many factory and mining industries contain high levels of toxic heavy mextals and organic contaminats. Adsorption is one of the simplest and cheapnest method, among the physical and chemical treatment method. In this investigation, the possibility of removing organic and mextal contaminants by bauxite nanoparticles was consideerd. So removal of the Basic Red-46, Basic Violet-10 dyess; Ni, Co ion from aqueoue solution; Cu and Mn from binary sewage were exmined. During the removing expriments the effective parameters such as pH, temperature, time contact, initial concentration, dosage adsorbent were investigated. Experiment data were fitted by Langmuir, Freundlich, temkin isotherm models and pseudo-first order, pseudo-secound order and intra particle diffusion kinetic models. baxsed on the result, in all expriments the pollutant removal were increased with increasing dosage of adsorbent and decreasing of initial concentration, during the time balance (approximately 120 minutes) to reach desorption pollutants, removal increases and the remains constant. Removal efficiency for BR-46 was determined %57.28 within exothermic reaction in the follow condition: (pH 5, temprature 21˚C, basic red 46 solution concentration 20 ppm and adsorbent dosage 0.2g). With the same conditions of temperature, concentration, dosage of adsorbent, and pH 6.5 removal efficiency of %53.66 for Basic Violet-10 whit in endothermic reaction respectively. Removal efficiency was determined %97.85 for Ni and %97.09 for Co in endothermic reaction in the following condition: (temperature=20◦C, adsorbent dosage=0.2g, pH=6.29 for Ni ion, pH=7 for Co ion). Cu and Mn wastewater removal obtained efficiency of approximately %99/68 for Cu and %88.32 for Mn.