Abstarct: Due to the increasing use of nanomaterials in the concrete industry, there are many researchers in this field. One of the newest nanomaterials - the use of micro-nano-bubbles (MNB) - as a supplement to water, can be used to have special effects in concrete properties. Some of these effects can be used to improve or weaken the properties of hardened and fresh concrete. One of the effects observed in concrete containing MNB has been the reduction of concrete workability. Due to the properties of super-plasticizers, using of it can have an effective role in reducing some negative effects of MNB on concrete properties. This research has investigated on coincident effect of using MNB and super-plasticizer on mechanical properties of concrete. This research has two parts, in the first part, the effect of MNB on mechanical properties of concrete was studied that 4 mixing designs with water to cement ratio (0.35, 0.4, 0.5, and 0.6) for making concrete have been used, then in the second part, the effect of MNB in presence of 3 super-plasticizer concentrations (0.5%, 0.9%, 1.4%) on the mechanical properties of concrete were studied that 3 mixing designs with water to cement ratio (0.4, 0.5, and 0.6) for making concrete have been used. For this purpose, 16 samples of cement paste for setting time test, 16 samples of cement mortar for flow of hydraulic cement mortar test, 48 samples of cement mortar for compressive strength of mortar test, 60 samples of concrete for concrete slump test, 156 samples of concrete for compressive strength of concrete test, 96 samples of concrete for tensile strength test and 12 samples of cement mortar for accelerated mortar bar test, were prepared and tested. The results of the experiments showed that MNB caused to accelerate setting time of cement, reduced concrete workability and mortar flowability and increased compressive strength considering to the amount of cement at the age of 7 and 28 days. Also, adding super-plasticizer in the presence of MNB in concrete showed that setting time of cement paste increased and concrete workability (W/C=0.4) in comparison with the samples containing MNB increased by an average of 50% and the 7-day compressive strength of concrete at concentrations of 0.5 and 0.9% has increased and compressive strength of concrete the age of 28 and 90 days at 3 concentrations of the super-plasticizer has decreased.