Abstarct: One of the biggest problem for large diameter pipelines during earthquake is rupture. For this reason checking intersections between faults and pipelines and Seismicity of the territory is very important and can be used in design, maintenance and crisis management. The hazards of wave propagation and Peak Ground Displacements (PGD) cause failure of buried water pipelines, wastewater and gas pipes during big earthquakes and they can not resist against shear deformations. Considering the importance of Mamloo dam water pipeline with 35 km length, 1800 mm diameter and flow rate of more than 2.5 m³ per second which is one of the main pipelines of drinking water resources of Tehran, and also according to Seismicity of this region, this pipeline is investigated for earthquake risk analysis caused by local faults. There are two method for earthquake risk analysis, Deterministic Seismic Hazard and Probabilistic Seismic Hazard. The Probabilistic Seismic Hazard method is used in this research. In this method at first the earthquake catalog including earthquake history information like date of occurrence, intensity and place of occurrence are obtained and then distribution chart of earthquake information is drawn. Using statistical analysis and linear regression, a line is fitted to the calculated distribution to obtain the parameters of Gutenberg-Richter relation. Using the acquired distribution, the favorite site is analyzed. According to the results, it is proposed to use thicker continuous pipes with high-strength ductile material for reducing the earthquake hazards.