Abstarct: Use of high levels of chemical fertilizers resulted severe environmental contamination, such as soil and water pollution. Organic fertilizers are used to decrease the pollution. In this context, a field experiment baxsed on randomized complete block design (RCBD) with three replications was carried out to compare application of vermicompost, urea and their combinations in research farm of Shahrood University of Technology (Iran) in April 2010. Five levels of N fertilizers (control, 100% vermicompost, 66.6% vermicompost + 33.3% urea, 66.6% urea + 33.3% vermicompost and 100% urea) were used in two landraces of corianders (Hamedani and Isfahani). According to the results, interaction effects between fertilizer treatments and landraces on seed yield, biological yield, harvest index, essential oil percent and essential oil yield were significant. Also, the comparing of interaction effect’s means between fertilizer treatments and landrace values indicated that the highest increase in interaction effect, is associated with 66.6% vermicompost + 33.3% urea in Isfahani landrace, and the lowest level is associated with control (no fertilizer), respectively. Yield and yield components were significantly affected by fertilizer treatment, where the highest levels observed in 66.6% vermicompost + 33.3% urea, and the minimum amount were associated with treatment without fertilizer. The effect of two landraces was significant only in percent of essential oil; it means that Hamedani landrace resulted in the highest value for percent of essential oil. In conclusion, quantitative traits showed different responses to landraces, fertilizer levels and their interactions. Interaction effect of landrace and fertilizer levels was significant on Linalool, the most important compound of coriander’s essential oil. According to the results, vermicompost can replace the bulk of urea fertilizer in cultivation of coriander as a medicinal plant. It’s a step towards sustainable agriculture and environmental protection.