Abstarct: In this experimental research, we are investigated surface morphology, structural, thermo-electrical, electrical and optical properties of nanostructured copper sulfide (CuS) thin film under different chemical bath deposition (CBD) conditions for photoconduction properties application. For characterization of synthesized samples we have used various equipment including: Field Emission Scanning Electron Microscopy (FESEM), X-ray diffraction (XRD), Raman Spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy, Seebeck effect and current-voltage (I-V) measurement. In order to prepare CuS thin films an aqueous solution including: copper chloride (CuCl2.2H2O), triethanolamine (TEA), ammonia (NH3), sodium hydroxide (NaOH), thiourea (SC (NH2)2), and distilled water was used. Variable parameters in this study are as following: the pH solution and annealing effect (Section 4-2), type of the substrate (Section 4-3), and concentration of copper chloride solution (Section 4-4). Depending on the growth conditions, the FESEM images of the samples indicated the formation of relatively uniform spherical grains, less than 100 nm in size, on the surface of the film. The results of X-ray diffraction pattern as well as thermoelectric properties indicate the formation of amorphous structure and p type electrical conductivity of all films, respectively. It was found that among the studied parameters, the band gap of the samples prepared on various substrates were changed due to the influence of quantum confinement effect as a result of the formation of fine grains in the laxyer. Also we found that the photoconduction sensitivity of the samples mainly depends on the band gap and the surface morphology of films.