Abstarct: In this experimental research work we have studied morphological, structural, optical and electrical properties of nickel oxide nano-grains thin laxyers of pure and doped grown by spray pyrolysis method. For physical characterization of samples we have used field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), UV-Vis.-NIR spectroscopy, current-voltage measurement and Seebeck effect experiment. In fabrication of NiO laxyers produced by NiCl2+6H2O powder various parameters were investigated. These parameters are including: the precursor volume, spray rate plus annealing in the air atmosphere, and finally the doping effect with Cu and Li atoms, i.e. NiO:Cu and NiO:Li.