Abstarct: Today dental implants are one of the best methods in treatment of lost teeth. A dental implant is a mextal screw especially made of titanium alloy that is inserted into the jawbone by a dentist as the root of the tooth and a crown is placed on it. The materials used are one of the important factors in the stability and lifelong treatment and the persistence of teeth in the long term. Mechanical and biocompatibility properties of implants are affected by the manufacturing method and surface conditions and material of the implants. Here, pure titanium samples and Ti-Al2O3 and Ti-Al2O3-HA composites were first fabricated by spark plasma sintering at 1200 ºC and 1300 ºC and 40 MPa pressure for 5 minutes. Titanium-Alumina-Nano hydroxyapatite composite made by spark plasma sintering (SPS) method for dental implant application, in order to investigate mechanical and biocompatibility properties density, hardness, pressure, corrosion and MTT tests. The results showed that by increasing the sintering temperature from 1200 C to 1300 ͦC the density of the samples increases and the apparent porosity decreases for making Ti-Al2O3 and Ti-Al2O3-HA composites. Adding alumina and hydroxyapatite to titanium also improves corrosion resistance. Hardness has improved in samples containing alumina and hydroxyapatite ceramics compared to pure titanium. The compressive strength of titanium is at its highest rate and the compressive strength of Ti-Al2O3-HA is improved compared to Ti-Al2O3. According to the results of MTT test, the Ti-Al2O3-HA sample has the highest biocompatibility among the samples and for the pure titanium sample and the binary sample, the biocompatibility has decreased, respectively. Addition of hydroxyapatite has improved biocompatibility and the survival rate of cells in the presence of composites containing hydroxyapatite has been very satisfactory.