Abstarct: Ti-6Al-4V is the most important used titanium alloy. High corrosion resistance, proper mechanical properties and bio-compatibility makes this alloy popular for medical uses such as, making Dentistal and Erthopedical Implants. The greatest drawbacks (disadvantages) of this alloy are low wear resistance, low fatigue resistance and poor tribological properties. The aim of this study was to apply an adhesive coating to improve both corrosion and wear properties of the Ti-6Al-4V alloy. To do this, surface modification of samples as done by nitrogen plasma in both electrolyte plasma and atmosphere plasma environment. Finally, the TiN laxyer was coated on the modified samples, using cathodic arc deposition technique. Micro-structure and coating thickness were measured (analyzed) using field emission scanning electron microscope (FESEM). The grazing Incidence X-ray diffraction (GIXRD) was applied to study the phases in the coating. Surface roughness of samples was determined by atomic force microscopy (AFM) analysis. The Corrosion resistance was studied with electrochemical impedance and TOFEL tests in Ringer solution. Pin-on-disc test was carried out to the wear resistance of the samples coefficient of friction was tested with Pin-on-disc machine.The toxicity and compatibility of coatings was evaluated with biocompatibility and MTT tests in vitro. The corrosion resistance of the samples was improved with applying the coatings. The PN-TiN sample showed the best corrosion resistance with current density of 6/857 ×10-7 A/cm2 and corrosion potential of -0/369 V. On the other hand, the lowest thickness reduction in wear test was observed in double laxyer coatings, so that the thickness reduction for both double laxyer coatings was less than 4 μm after 300m sliding. In vitro biocompatibility studies performed using bone marrow stem cell demonstrated that the coatings are non-toxic and exhibit excellent cell- materials interactions.