Abstarct: Copper, as one of the most important non-ferrous mextal elements, has wide applications in various industries. The main sources of this mextal include sulfide, oxide, and mixed sulfide-oxide deposits, for which different processing methods are proposed depending on the type of mineralization. Among the main methods of copper extraction are flotation, leaching, and bioleaching. In mixed sulfide-oxide deposits, the order of implementation of the processes (flotation and then leaching or vice versa) depends on the percentage of sulfide, oxide, and associated tailings. Supplementary methods such as sulfidation and pulp preparation before flotation are also used in some cases. In this study, leaching and flotation methods were used to extract copper from samples prepared from the oxide and sulfide zones of the Chehel-Koure copper mine, respectively. First, representative samples were prepared from both zones. Then, samples were crushed for leaching tests using jaw and roller crushers so that the particle size was between +1000 microns and +500. Also, samples were crushed to a degree of freedom (37 microns) using the above crushers and a laboratory ball mill. Sieve analysis of the samples, assay, XRF, XRD and atomic absorption analyses were performed on the samples. Copper recoveries were calculated for both zones and the recovery values were compared. The results showed that the maximum copper recovery in the leaching method and for the oxide zone is 74.15%, while the maximum copper recovery in the flotation method and for the sulfide zone is 97.84%. As a result, it can be said that the flotation method is much more effective than the leaching method for extracting copper ore from the Chehelkooreh mine in Zahedan.