Abstarct: Abstract Human societies are facing the limitation and shortage of energy sources such as oil, gas and coal, and the damage caused to the environment by these sources is not hidden from anyone. In most domestic and industrial heating and cooling systems, energy consumption, system inefficiency and energy waste include a large percentage of biological pollution and economic costs. In this research, supercritical hybrid refrigeration system was designed and energy and exergy analysis was done on it and the results were reported. The system consists of a supercritical CO2 refrigeration cycle (VCRS) and a refrigeration cycle including two ejectors (VERS) with R32 refrigerant, whose energy analysis was done using EES software. The amount of exergy destruction of the system components has been calculated and compared with the results of previous works and validated, and little changes are observed in the values. Certainly, the working conditions of the first cycle limit the choice of refrigerant for the second cycle, in which R32 refrigerant shows the highest efficiency. At the evaporator temperature of 5°C, the performance efficiency of the hybrid refrigeration system using two ejectors has increased from 2.27 to 2.33 compared to the simple single loop VCRS refrigeration system, i.e. 2.5% of the performance efficiency (COP) of the system has increased.