Abstarct: Bitumen is the main element of asphalt mixture and viscoelastic material and its mechanical response depends on temperature and loading time. The asphalt pavement should not be too hard to operate during its design period. Researchers in this field believe that the most important factor of these changes is the gradual hardening phenomenon that causes the appearance of various types of injuries in the pavement. Various processes are involved in the gradual change or hardening of bitumen, including oxidation, photochemical reactions, substrate of volatile matter and bitumen, polymerisation, carbonization and absorption of oils in bitumen by aggregates. In this research, the effect of nanozinkoxide and nanoclay and the combination of two materials on the behavior of bitumen aging in softening point, penetration, loosen heating, bitumen viscosity and viscosity aging index are studied. The results of this study showed that the addition of nanozinkoxide to 1.4% in both the pre and post aging conditions increased the softening point and thus improved bitumen performance at high temperatures. The performance of modified bitumen with the combination of nanomaterials showed that bitumen containing 1.4% nanozinkoxide plus 2% nanoclay in an aged state had a higher viscosity than the Original Bitumen. Also, the addition of nanoparticles to bitumen increases the viscosity in the two aging states of RTFO and PAV. In addition, bitum containing 1.4% nanozinkoxide and 2% nanoclay have a lower VAI index than pure bitumen. In fact, nanomaterials have reduced bitumen aging in RTFO mode. The results of PAV samples also show that the addition of nanoparticles decreases the aging index.