Abstarct: One of the most important environmental issue is the contamination of water resources by oil pollution. The main goal of this study was to study the removal of gasoline from aqueous solution using Micro-Nano bubbles (MNB) and Zero-Valente Iron (NZVI) Nanoparticles. In reduction of COD of soluble fraction of gasoline in aqueous solution, the effect of pH and initial concentration of the pollutant by MNBs and also the effect of pH, contact time, dosage of adsorbent and initial concentration of the pollutant in the adsorption process by NZVI were investigated. The result showed that the maximum percentage of COD reduction related to soluble fraction of gasoline in aqueous solution by MNBs that was occurred at the following condition of pH=7, contact time=5 min and initial COD=500 ppm was 91%. Reduction of COD associated with the soluble fraction of gasoline in water in the adsorption process by NZVI under the following condition was 95%: pH=3, contact time=60min, dosage of adsorbent=0.1 g/L and initial COD=100 ppm. Also, the result indicated that MNBs had no significant effect on TDS reduction of the wastewater polluted with gasoline and NZVI removed 113 ppm of TDS of the samples at the following condition: pH=3, contact time=120 min, dosage of adsorbent=0.1 g/L and initial COD=1500 ppm. The experimental data from adsorption process by NZVI was fitted to the Langmuir adsorption isotherm model and followed the pseudo second order kinetics. The mechanism of COD reduction of soluble fraction of gasoline in aqueous solution using MNBs and NZVI were investigate through SEM, XRD, DLS, and measurement of Zeta potential and mobility.