Abstarct: Salinity and water scarcity are the main challenges to maintain global food security. The use of nutrients in formulations is a new fertilization strategy for crops. In this study, to investigate the effect of foliar spraying of zinc chelate and calcium oxide on some physiological and agronomic characteristics of corn plants under soil salinity conditions, a factorial experiment was conducted in the form of a randomized complete block design with 3 replications in 1401 in one of the fieldsin south of Semnan city (Iran). The factors of the experiment were included zinc chelate at three levels (0, 2 and 4 cc/liter) and the second factor included calcium oxide at three levels (0, 3 and 6 cc/liter). BC678 variety of corn, which is a mid-ripening variety, was also selected. The foliar sprays were done separately before flowering in two stages with 5-day intervals. The first stage was foliar spraying with zinc chelate, then 5 days later foliar spraying was done with calcium oxide, again for the second stage 5 days later foliar spraying was done with zinc chelate and finally 5 days later the second stage was foliar spraying with calcium oxide. . The results of this research showed that the interaction effect of zinc chelate and calcium oxide on cob length, leaf surface index and catalase enzyme was significant, but the results showed that calcium oxide and zinc chelate on the number and width of leaves, the relative content of leaf water and diameter. The cob became insignificant. Application of calcium treatment increased all three types of chlorophyll a, b and total. Also, foliar spraying with concentrations of 4 and 6 cc per liter of zinc chelate and calcium oxide increases the weight and length of ears, dry weight of aerial parts, weight of one hundred seeds, leaf area index, Calcium and zinc in leaves, proline and anti enzymes. Oxidized. In high concentrations of calcium oxide, a decrease in leaf dry weight was also observed, but in high concentrations of zinc chelate, the amount of calcium in leaves increased significantly. The yield of seeds was obtained as a result of foliar spraying with a concentration of 6 cc/liter of calcium oxide, 8.32 tons per hectare, which increased by 68.76% compared to the control. Therefore, in order to overcome the negative effect of salinity stress, it is inevitable to use calcium ion and zinc element in the growth medium to improve the stress factor. In total, these findings showed that foliar spraying with concentrations of 4 and 6 cc per liter of zinc chelate and calcium oxide, respectively, is useful for reducing the effects of salinity stress on corn plants grown in saline soil.