Abstarct: Abstract This study was conducted to investigate the effect of abscisic acid (ABA) and gibberellic acid (GA) on quantitative and qualitative characteristics of bread wheat under low irrigation conditions in the 97-98 crop year in Shahrood. The experiment was performed as a split-factorial plot in the form of completely randomized blocks with three replications. Treatments included three levels of irrigation in the main plots including optimal irrigation, interruption of an irrigation period at 50% flowering and 50% grain filling stages as a main plot and two levels of abscisic acid and gibberellic acid in sub-plots (zero and 100 ppm). The results showed that the interaction of drought stress, abscisic acid and gibberellic acid on morphological, yield-related and physiological traits of wheat was significant at the level of one percent. Drought stress effectively reduced heightplant, spike length, number of seeds per spike, 1000-seed weight, grain yield, chlorophyll content and increased ascorbate peroxidase, guaiacol peroxidase, catalase and malondialdehyde content. Application of different levels of abscisic acid and gibberellic acid and their simultaneous application had completely different effects on the evaluated traits. In most cases, the application of gibberellic acid or the simultaneous use of abscisic acid and gibberellic acid reduced or moderated the adverse effects of low irrigation stress on wheat. Overall, the results of this study revealed that wheat in the growth stage of 50% grain filling compared to the 50% flowering stage is less sensitive to low irrigation stress. In case of water restriction, we will be able to prevent the negative effects of low irrigation stress by using gibberellic acid or the simultaneous use of abscisic acid and gibberellic acid.