Abstarct: During recent decade, the use of chemical inputs in agricultural lands has caused some main environmental problems such as fertility reduction, soil salinity, imbalance of mextals in soil and contamination by some heavy mextals .in order to study the effects of the Arsenic lead and salinity stress on chemical propertices of the soil and of growth in sorghum (notrofild), a plot experiment was carried out in the Agriculture colleage of the Shahroud university technology in 2015. The study designed in from completely randomized block design with 3 replication. The treatments of the experiment, included four levels of salinity: control, 3, 6, 9 dS/m, and Arsenic treatment included four levels : control (without use Arsenic), 20, 40, 60 mg/kg soil. The salinity stress from the four-sheet stage was applied on the plant by using NaCl. The results indicates that the effect of salinity reduced fresh and dry weight of the plant and amount of chlorophyll a and b was reduce. The least amount of fresh and dry weight and chlorophyll a and b were observed in 9 dS/m. The salinity increases Anthocyanin pigments, guaiacol peroxidase enzyme activity in root, shoot sodium concentration. The study showed arsenic, catalase enzyme increased shoot activity. It was also found that arsenic decreased plant dry weight at first and then increased it. In the interaction of salinity and arsenic, guaiacol peroxidase enzyme activity was affected shoots. Arsenic increased with increasing salinity, guaiacol peroxidase activity was increased. About the impact treatments on soil chemical properties, electrical conductivity and soil pH showed significant effects of salinity on the highest electrical conductivity and soil pH was observed in 9 dS/ m.