Abstarct: In order to investigate the effects of sulphur fertilizer in 3 levels (non-application 200 and 400 kg.h) application of flomix in soil in 2 levels (application and non-application) and foliar application of flomix in 2 levels (apication and non-application) on growth and yield of sesame plant in weeding and non-weeding conditions ,an experiment was conducted in research field (located in 15 kilometer road to sari) in 1393 .the research was designed as factorial baxsed on completely randomized blocks in 3 replications.the results indicated that the main effects of the factors were significant when weeding was done while the best treatment was the triple effect of 200 kg.h sulphur application soil application of flomix and flomix plant capsule length, number of seeds per capsule and harvest index indicated significant and pisitive correlation with seed yield in 1 percent level of possibity. further more, the outcome presented that the highest yield was obtained when flomix used as soil fertilizer according to the table of correlatipn coefficient the final plant height and also number of capsule in plant showed a significant and positive correlation in 5 percent level of possibility what is more percent of seed oil and protein content in both (weeding and non-weeding) had no significant effect. assessing the weed dry weight indicated the highest amiunt in foliar application of flomix.