Abstarct: This study aimed to evaluate the effect of tillage management and salicylic acid on agronomic characters and yield of sorghum (Sorghum bicolor L.) at mycorrhizal symbiosis condition was carried out in the Agriculture Research Station of Shahrood University in crop year 2013-2014. An experiment was carried out as Split-Plot factorial baxsed on Randomized Complete Block Design (RCBD) with three replication. In this study, the main Plot was different levels of tillage systems In the three levels: 1- conventional tillage (Moldboard+disk+ Furrower), 2- reduce tillage (disk+Furrower) and 3- minimum tillage (Chisel+Furrower), the combination of levels priming with salicylic acid at 2 levels: (non- priming and priming) and mycorrhizae symbiosis at 2 levels (non-application and application of mycorrhiza) were considered as subplots. baxsed on the results, interaction between different levels of tillage systems and priming with salicylic acid was significant on 1000-seed weight, chlorophyll b traits. The result showed that, interaction between different levels of tillage systems and mycorrhizae symbiosis was significant number of fertile panicle, chlorophyll traits. Also, The result showed that, interaction between priming with salicylic acid and mycorrhizae symbiosis significantly increased root colonization and chlorophyll a. Moreover, traits of grain yield, biologic yield, HI and chlorophyll b was affected by interaction between different levels of tillage systems and priming with salicylic acid and mycorrhizae symbiosis. baxsed on mean comparisons, treatments combination of conventional tillage+ priming with salicylic acid increased grain yield 0.17 T/ha in compared with minimum tillage+ non-priming with salicylic acid. Also, treatments combination of conventional tillage+ priming with salicylic acid increased 1000-seed weight, and chlorophyll b respectively, 68 percent and 0.56 Mg/gr in compared with minimum tillage+ non-priming with salicylic acid. Also, treatments combination of conventional tillage+ Mycorrhizal inoculation increased chlorophyll b and number of fertile panicle respectively, percent, 0.43 Mg/gr , 2.5 number of fertile panicle. baxsed on mean comparisons, root colonization increased from 34.22 percent in treatments combination of priming with salicylic acid+ non- inoculation of mycorrhiza to 55.83 percent in priming with salicylic acid+ Mycorrhizal inoculation and also treatments combination of priming with salicylic acid+ Mycorrhizal inoculation increased chlorophyll a equivalent to 0.55 Mg/gr in compared with non-priming with salicylic acid+ non-inoculation of mycorrhiza. Mean comparisons showed treatments combination of conventional tillage+ priming with salicylic acid+ Mycorrhizal inoculation increased HI 18.79 percent in compared with minimum tillage+ non-priming with salicylic acid+ non-inoculation of mycorrhiza. Also, treatment combination of conventional tillage+ priming with salicylic acid+ Mycorrhizal inoculation increased grain yield and biologic yield respectively, 0.52 , 0.65 T/ha in compared with minimum tillage+ non-priming with salicylic acid+ Mycorrhizal inoculation and reduced tillage+ priming with salicylic acid+ non-inoculation.