Abstarct: In this study the effects of the plant growth regulators on micropropagation of several Iranian apricot’s cultivars was investigated in order to achieve high capacity of propagation by tissue culture. The shoot explants of “Jafari”, “Ghavami”, “RajabAli” and “Khiveei” apricot’s cultivars were provided from a training orchard in agriculture department of Shahrood University. The Nodes after surface sterilized with HgCl and citric acid were establishments in the MS and WPM mediums. The results of the two media did not show a significant difference in the apricot bud sprouting. The average of Rajabali cultivar bud sprouting percent in removed scales bud was 62.77 in dormant winter shoots and 76.66% in the vegetative spring shoots. Proliferation of bud sprouting explants examined on WPM medium supplemented with three concentrations of (0.5, 1 and 2) mg/l BAP and IBA at 0.05 mg/l in several varieties of apricot. The maximom shoot number and shoot length obtained at concentration of 1 mg/l in “RajabAli” apricot cultivar and 2 mg/l of BAP “Jafari” apricot cultivar, respectively. In order rooting of proliferation shoots, three concentrations of IBA (0.5, 1 and 2 mg/l) were examined. The results of rooting experiment were not successful and lost explants.