Abstarct: Indole derivatives and 1,2,3-triazoles have a broad of biological activities such as anti-inflammatory, anti-bacterial, anti-HIV, anti-fungal and anti-cancer. In this study, a new derivatives of indole-baxsed 1,2,3-triazole derivatives are synthesized by the reaction of 2-aryl-1-(prop-2-ynyl)-1H-indole-3-substituted with aromatic azides via copper-catalyzed click reaction of copper(II) acetate and sodium ascorbate in ethanol at 70 ºC. All synthesized compounds were characterized by 1H-NMR, and 13C-NMR analysis.