Abstarct: Polyhydroquinolines are important compounds which show a wide range of biological activities such as anti-tumour, antibacterial, anti-tuberculosis, anti-AIDS and anti-viral. In this study, various derivatives of polyhydroquinolines were synthesized via a one-pot four component reaction of ammonium acetate, aromatic aldehydes, ethyl acetate and diademone or cyclohexadiazone in the presence of PVC-Cys-ZnCl under solvent-free conditions at 80°C. In the second part of this study, new derivatives of 1,2,3-triazoles lixnked-polyhydroquinoline were synthesized in the presence of copper acetate catalyst and ascorbate sodium in ethanol by click reaction. The structure of catalyst was studied by FT-IR, CHNS, ICP and Fe-SEM analysis and the structure of all new compound were identified by 1H-NMR, 13C-NMR and IR spectra.