Abstarct: Reaction of ethyl 4-oxo-3,4-dihydroquinazoline-2-carboxylate and related amide compounds with propargyl bromide afforded ethyl 4-oxo-3-(prop-2-yn-1-yl)-3,4-dihydroquinazoline-2-carboxylate and amide propargylated compounds. Treatment of prepared compounds with aromatic azides or sodium azide and benzyl chloride in the presence of copper(II) acetat, 4-amino-5hydroxy naphthalene-2,7-disulfonic acid mono sodium salt as a ligand and sodium ascorbate in water afforded new derivatives of 1,2,3-triazole-lixnked quinazoline-4-one scaffold with good-to-high yields.