QD276 : The synthesis of Triazole derivatives Catalyzed by eggshell-supported-CuI
Thesis > Central Library of Shahrood University > Chemistry > MSc > 2016
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Abstarct: Since 1,2,3-triazoles have various biological characteristics such as anti-inflammatory and anticancer. Therefore using novel methods for synthesis of new derivatives is of great importance. In this work, a new heterogeneous catalyst was prepared baxsed on Cu-Metformin complex immobilized on the Eggshell. Then 1,2,3-triazole derivatives were prepared as one pot via reaction of alkyl halides, terminal alkyne and sodium azide in the presence of catalyst and water as solvent within 60 min. Facile purification, using water as solvent, high yield and short reaction time are the advantages of this method.
Keywords:
#1 #2 #3-triazole #Cu-Metformin #one pot reaction #sodium azide Link
Keeping place: Central Library of Shahrood University
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Keeping place: Central Library of Shahrood University
Visitor: