Abstarct: One-pot multi component reactions (MCRs) are an attractive synthetic strategy to generate multiple molecular scaffolds and to increase structural as well as skeletal diversity from simple and easily available molecules. Activation of a terminal alkyne C–H bond by transition mextal catalysts is a reaction of fundamental interest in organic synthesis . One of the best examples of such a process is three components coupling of aldehydes, alkynes, and amines (A3-coupling). we report an efficient three-component coupling of aldehydes, amines, and alkynes catalyzed by nano boehmite-CuI.