Abstarct: Use of zirconia as a catalyst and a catalyst support has increased manifold over the past decade. Zirconia powder has been exploited as a catalyst in a variety of reactions like alkylation, amination, condensation, isomerization, cracking, hydration and oxidation. Partial oxidation of alkenes to epoxides and reaction products baxsed on epoxides are both of academic and industrial interest. Various epoxides are among the most widely used intermediates in organic synthesis, pharmaceuticals as well as polymer production. In order to make the epoxidation process cleaner, safer and more efficient, the use of catalysts is mandatory. In this work we have been used sol-gel derived nano-zirconia as catalytic bed. Then, this inorganic bed was covalently functionalized by refluxing nano-zirconia with 3-(trimethoxysilyl)propyl amine in toluene (AFNZ). Functionalized zirconia, then was refluxed in a solution of MoO2(acac)2 in CHCl3 and mextalated catalyst, Mo-AFNZ, was prepared. CHN and ICP analysis showed that the amount of nitrogen and Mo loading on Mo-AFNZ are 0.632 and 0.353 mmol/g respectively. Mo-AFNZ also was characterized by FT-IR, TG-DTA and TEM technique. Then Mo-AFNZ was used as catalyst for the epoxidation of cis-cyclooctene and yields of products were investigated by GC. The catalytic procedure for this reaction were optimized for different parameters such as amount of catalyst, type and amount of solvent, type and amount of oxidant and time. It was found that the optimized conditions with this heterogeneous nano-catalyst were 25 mg Mo-AFNZ, 2 ml chloroform as solvent, and 1.12 mmol tert-butyl hydrogen peroxide as oxidant.