QD174 : Bohemit-nanoparticle-promoted synthesis of polyhydroquinoline derivatives via multicomponent Hantzsch reaction
Thesis > Central Library of Shahrood University > Chemistry > MSc > 2013
Authors:
Abstarct: Polyhydroquinolines are important compounds which show a wide range of biological activities such as Ca2+ channel blockers, antitumour, antidiabetic antiatherosclerotic. Polyhydroquinolines were synthesized via a one-pot four component reaction in moderat to high yields. In this method a mixture of ammonium acetate٫ aldehyde and ethyl acetoacetate and dimedon or syclohexa1,3-dion in the presence of boehmite under solvent-free condition at 80°C were reacted to give the corresponding Polyhydroquinolines.
The boehmite is non-toxic, inexpensive and, Spectroscopic data of the products are included in appendix.
Keywords:
#four component reaction #Polyhydroquinolines #Nanoboehmite #solvent-free Link
Keeping place: Central Library of Shahrood University
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Keeping place: Central Library of Shahrood University
Visitor: