QD125 : Synthesis of syntesis of phthalazines drugs catalyzed by nano bohemite
Thesis > Central Library of Shahrood University > Chemistry > MSc > 2012
Authors:
Ameneh Hadi [Author], Mohammad Bakherad[Supervisor], Hossein Nasr Isfahani[Advisor]
Abstarct: We have described one-pot solvent-free rapid and efficient method for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives via the nanoboehmite catalyzed reaction of aldehyde, malononitrile, and phthalhydrazide at 120 °C. the simplicity of the system, ease of separation/reuse of the catalyst and ease of work-up make the described method for the synthesis of 1H-pyrazolo[1,2-b]Phthalazine-5,10dione an attractive, which can be extended to the synthesis of other heterocyclic compounds.
Keywords:
#One-pot #Solvent free #Pyrazolophthalazine #Nanoboehmite Link
Keeping place: Central Library of Shahrood University
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