QD117 : Multi component synthesis of imidazole drugs by nano-bohmite catalyst in solvent freecondition
Thesis > Central Library of Shahrood University > Chemistry > MSc > 2012
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Abstarct: 1٫3-Diazoles were synthesized via a one-pot three or four component reaction in moderat to high yields. In this method a mixture of benzil٫ ammonium acetate٫ benzaldehyde and various aliphatic and aromatic at 120˚C and non-solvent conditions were reacted to give the corresponding imidazoles. Imidazoles are important compounds which show a wide range of biological activities suchas; Anti fungal and Anti-bacterial activity٫ Anti inflammatory activity and analgesic activity٫ Anti tubercular activity٫ Anti depressant activity٫ Antileishmanial activity٫ Anti viral activity٫ Anti cancer activity.
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