Abstarct: 1٫3-Diazoles were synthesized via a one-pot three or four component reaction in moderat to high yields. In this method a mixture of benzil٫ ammonium acetate٫ benzaldehyde and various aliphatic and aromatic at 120˚C and non-solvent conditions were reacted to give the corresponding imidazoles. Imidazoles are important compounds which show a wide range of biological activities suchas; Anti fungal and Anti-bacterial activity٫ Anti inflammatory activity and analgesic activity٫ Anti tubercular activity٫ Anti depressant activity٫ Antileishmanial activity٫ Anti viral activity٫ Anti cancer activity.