Abstarct: This research investigates the effects of air pollution and the use of renewable energies on healthcare costs in OPEC+ Plus member countries. Statistical analyses, including multiple regression, correlation tests, and fixed and random effects tests, show that air pollution (AIRP) has a significant and positive correlation with increased health costs, while the impact of particulate matter concentration (PM2.5) on treatment costs cannot be confirmed. Furthermore, the results indicate that reducing air pollution can lead to economic savings and improved population health, but the impact of renewable energies on reducing healthcare costs is not confirmed at a 95% confidence level. Factors such as the long time required for long-term effects, the limited share of renewable energies, and the oil-baxsed economic structure may contribute to this insignificance. The findings of this study emphasize the need for effective policies in controlling air pollution, developing healthcare infrastructure, and long-term planning for the sustainable use of energy resources, in order to reduce economic and social pressures on the healthcare system and achieve continuous improvement in public health indicators.