Abstarct: The general objective of this research is to investigate the effects of corporate social responsibility and total quality management on the organizational performance with the mediating role of innovative performance and manufacturing flexibility in shiraz Iran khodro company. The research method is descxriptive of survey type. The statistical population of this research includes all experts and specialists of shiraz Iran khodro company. Using a simple random sampling method,181 individuals were selected as the sample of the study. Data were collected through a questionnaire. The content validity of the questionnaires was used by the experts opinion and using the AVE values, the validity of the measurement tool was confirmed. Reliability of the questionnaires was also calculated through CR and Cronbach’s alpha. Data were analyzed using descxriptive statistics such as mean, standard deviation, abundance, frequency and inferential statistics such as correlation matrix, path coefficients, t statistic and sobel test. The result of the correlation and partial least squares test confirm this issue that the variables proposed in this model correlate and have a significant correlation. As well as the result of the hypothesis test indicate that all research hypotheses are approved.