Abstarct: The purpose of this research was comparison of sensitivity to the taste of fat in athletes and non-athletes and it relationship with body composition. This study is a cross sectional study that To implement the research 55 students and staff to run the city of Qazvin (mean age 52/23 years old, height 77/1 meters, weight 48/72 kg, BMI 23 kg per square meter) as were targeted and selected. Then in two separate sessions the subjects were taken blood samples and tested. Tests including bloodletting, Body composition measurement by inbody machine and preference foods was assessed by questionnaire. In the first session of athletes and non-athletes with normal weight were tested and in the second session of none-athletes obese were tested. The main variable samples (Serum levels of CD36) was measured by assay kit made in Germany. Body composition and preference of foods and the general condition of each group were measured too. Average serum levels of CD36 in athletes (264/5 ± 162/94 ng / l), none-athletes with normal weight (486/7 ± 377/88 ng / l) and none-athletes obese (157/11 ± 23/59 ng / l) was that did not show significant differences (p <0/05). Average tend to high fat foods also in athletes (65/1 ± 21/57) higher than none-athletes with normal weight (50/59 ± 28/88) and none-athletes obese (41/05 ± 25/67) that had significant difference with obese group (p <0/05). Conclusion: The results of this study showed that there is an inverse relationship between serum levels of CD36 and body fat percentage, and according to lower body fat percentage in athletes, had higher levels of CD36 to compared with obese people and so, probably athletes have higher sensitivity to the taste of fat than non-athlete obese.