Abstarct: Coal is the fuel of the past and the future and in terms of energy production and other applications in the industry is the most important world's mineral resources. Declining oil reserves, energy crisis and the increasing demands of human bright horizons has outlined coal processing industry. Flotation is a method used for separating the valuable minerals fram waste materials. The factors affecting the coal flotation process can be pointed as: chemistry impacts (such as: type and amount of collector, type and amount of frother, etc.), coal characteristics (such as: particle size, petrography, mineralogy, etc.), machine characteristics (such as: type, gas hold up, carrying capacity, etc.). In this research, we focuse on chemistry impacts, Also finding the optimum values of them, as well as the possibility of replacing gasoil with kerosene as a collector (due to its lower price), is the main objective of this tesis. Using DX10 software and RSM, CCD are respectively study type and design type. Experiments was conducted five numeric factors with three surface for each factor and select six center point. thirty-two experiment was predicted. Responses was: recovery, separation efficiency and the ash content in flotation concentrate, So this responses was applied to evalute flotation efficiency. Results show that (With 90% desirability) optimum Factor values to access maximum efficiency (87.51%), maximum separation efficiency (26.08%) and minimum ash content in concentrate, include collector dosage (only gasoil): 1000 g/t, frother dosage: 158.34 g/t, pulp solid percent: 10.3%, particle size range distribution in (+355-1000) micron. During experiments some other factors was constant, such as: pH=7, scorification time in the case of using kerosene:2.5 minutes, gasoil: 3 minutes, 50% kerosene: 2.75 minutes, agitator speed: 1000 rpm, frother type: pine oil. By the way a new combination of fine coal and water Along with inappreciaable percent of resins introduced as a new collector, with the same design method (mentioned above), ten experiments done.other parametrs was just like that of thirty-two experiments, Except that scorification time and dosage of this new collector and frother (pine oil), was respectively: 2.5 minutes, 5 kg/t and 350 g/t. Two factors such as: "solid percent" and "particle size range distribution" considered to obtain maximum separation efficiency and minimum ash content in concentrate. Results with 90% desirability show that, maximum S.E. (27.82%) and minimum ash content transferred to concentrate (9.1%) impetrate in optimum factors, Pulp solid percent: 10.3% , particle size range distribution: (+355-1000) micron. Comparing the results of seperation efficiency and ash reduction amounts in the second manner, affirm the advantage of this collector.