Abstarct: The recovery of precious mextals from low grade is highly regarded sources. Laterite is a valuable source of mextals, particularly nickel and cobalt are. Leaching of nickel laterites to produce common-methods in extracting the mextal. South Khorasan is ferruginous tuff sample mineralogy was studied. The analysis showed that the sample containing 0.58% nickel, cobalt 0.0098% and 34.89% iron. The results of XRD analysis on the samples showed that the phases of nickel ore are goethite, hematite, magnesite, dolomite and silicates. The results show that the ammonia leach process instances by Caron, nickel extraction is small allotment. The leaching process was investigated with various acids, nitric acid is not effective in the recovery of nickel. Sulfuric acid concentrations higher than 600Kg/ton will result in the recovery of nickel and HCl at high-concentration (5M) has high recovery. Then various factors including temperature, acid concentration, time, solid content, sample size and additive were investigated on leaching to atmospheric acidity with sulfuric acid.. The increase of temperature, acid concentration and time increased recovery and increase the solid content of the sample size decreases the recovery of nickel. Effect of additive showed NaCl increases the recovery but K2SO4 and Na2SO4 no significant effect on recovery. Finally, experimental was carried out at optimize and economic conditions in 800 Kg/ton and 25 g/l chloride in temperature 90 oC. the recovery of nickel, cobalt, 100% and 40%, respectively.