Abstarct: Factors like increase in the world’s population and increase in energy consumption and the fossil fuels being finite and the rise in environmental pollution as a cause of using fossil fuels has significantly increased the need to use renewable energies more than ever. Because of the natural benefits of renewable energies these clean resources take more share in world’s total energy production every year. In this approach, to supply the required power load of a zone independent of the main network in state of Lorestan (15 homes close to the town of Khoram Abad) special attention has been given to modeling and optimization of renewable energy combination systems baxsed on solar energy, wind and water. Combination system comprised of energy production sources (solar panels, wind turbines, hydrokinetic turbine) and backup system (including energy saving battery and diesel generator(the purpose of optimization is to present an optimized combination system to supply load with minimum total cost and the most reliability and also the highest influence of renewable power with taking into consideration the technical and economical limitations. For these purposes, two optimized distribution strategies, load following and charging cycle have been proposed for designing integrated energy systems. In each one of the strategies, the effects of consumed fuel price changes of diesel generators and the initial cost of production for hydrokinetic turbines, solar cells, wind turbines and other components and interest rate changes on the optimized design of combination systems has been reviewed. Eventually optimized combination systems was compared and analised economically with other systems evaluated in the past.