Abstarct: In recent years, wasted heat released in environment is increased. Exhausted gas of turbines and motors and wasted heat in factories are some examples to point. These are now the principal environmental problems. To utilize these resources, retrieve the exhausted energy and decreasing the usage of fossil fuels and also for environmental cares, we have simulate a cycle of ejector refrigeration with vapor ejector in Hysys software and then energy and Exergy are evaluated. Applying and calculating the energy and exergy equations related to the parts of cycle, exergitic analysis of cycle is done. Through all parts of cycle maximum exergy destruction is related to boiler and after that is related to ejector. Also with parametric analysis, effects of designing parameters such as temperature and pressure of boiler, condenser temperature, mass ratio and ejector vacuum pressure on function of refrigeration cycle are calculated. Results shows that in boiler range temperature from 134 ° C to 145 ° C, efficiency of system (0.23 - 0.2277) and exergetic efficiency of system in range of 18.62% - 19.06% are decreased. In addition, in boiler range of pressure from 250 to 300 kpa, efficiency of system in range of 0.2298 – 0.2292 and exergetic efficiency of system in range of 18.45% to 19.4% are increased. Studying effect of condenser temperature shows that, increasing the condenser temperature in range of 25 ° C to 32 ° C, increase the efficiency of system in range of 0.2277 to 0.2298 is decreased and exergitic efficiency of system in range of 19.4% to 18.62% is increased. In condenser and boiler, it is observed that in mentioned range of temperature, by increasing ejector vacuum pressure from 0.9 to 1.2 kPa, efficiency of system in range of 0.2301 to 0.2275 increases and exergitic efficiency of system in range of 16.66% to 22.06% decreases. Also considering the mass ratio of ejector on cycle function shows that by increasing the ejector mass ratio from 0.11 to 0.47, efficiency of system in range of 0.11 - 0.47 and exergitic efficiency of system in range of 0.1021 - 0.4326 increase