Abstarct: Global concerns regard to global warming through producing greenhouse gases such as CO2 and the need for appropriate concrete resistivity against chloride ion penetration in marine constructions are among the reasons that numerous studies have conducted on using appropriate pozzolan as a substitution to the part of consumed cement in the concrete which improve mechanical properties and durability of concrete. This study evaluated the effects of using mexta-kaolin and zeolite as substitutions to part of consumed cement in the concrete, moreover, micro-nano bubbles of water were used as a substitution for mixing water in the concrete, the combination of optimal percentage of zeolite and mexta-kaolin in mixed with micro-nano bubbles of water. We examined the compressive strength (BS 1881), flexural strength (ASTM C78), tensile strength (ASTM C496), Percentage of water absorption in 30 minutes and 24 hours (BS 1881), electrical indication of concrete's ability to resist chloride ion penetration (ASTM C1202) and examination of hardened concrete using Scanning Electron Microscopy(ASTTM1723-16) .We cured concrete samples with drinking water, in standard condition of forming compound which consist of saturated water and lime, and as a case study, in standard condition of forming compound in artificial seawater according to the standards (ASTMD1141). The results of experiments indicated that using 10% of mexta-kaolin instead of part of cement in concrete samples caused to increase compressive strength, flexural strength, and tensile strength by 4.75%, 25%, and 1.97%, respectively. Moreover, in chloride permeability experiment, the chloride ion penetration reduced to 56.36% at the age of 28 days compared to control samples. In addition, in sample containing 10% zeolite, there were 3.7% increase in compressive strength and 4.34% and 16.6% decrease in water absorption 30 minutes and 24 hours of absorbing water, respectively. The samples contained micro-nano bubbles of water at a replacement rate of 50% and 100% instead of the water mixed concrete caused to increase compressive strength 8.82% and 13.2%, respectively, tensile strength 10% and 19.64%, respectively, and decrease of 16.8% and 20% in 30 minutes’ absorption water experiments at the age of 28 days, while compared to the control samples. The effects of using zeolite and mexta-kaolin simultaneously in mixture with micro-nano bubbles of water improved mechanical properties and durability of concrete. The best produced sample related to the combination of 10% zeolite and 10% mexta-kaolin in mixture with 100% micro-nano bubbles of water. This compound increased the mechanical properties of concrete in experiments of compressive and tensile strength to 14.85% and 18.37%, respectively. It also improved the durability of concrete in 24 hour experiments of water absorption and at the age of 90 days, chloride permeability decreased to 17.56% and 80.45% respectively, while compared to control samples. According to the results, in the sample made by 100% micro-nano bubbles of water cured in artificial seawater up to the age of 28 days, caused an increase in compressive strength, tensile and flexural strength of 6.97%, 10.71% and 11% compare to control samples which cured in samples formed in standard conditions. Also, in the mixed sample which contained 10% silt, 10% mexta-kaolin, in a mixture of 100% micro-nano bubbles of water cured in artificial seawater up to the age of 28 days, caused an increase compressive, tensile strength and flexural strength of 11.13%, 14%, and 9.1% and reduction were observed in chloride permeability and 24-hour water absorption of 15.19% and 7.86% compared to similar samples in standard forming condition.