Abstarct: In order to investigate the effects of different priming treatments on yield and yield components, physiological and biochemical properties of cowpea under different moisture conditions, this experiment was conducted as a split plot in a randomized complete block design with three replications in 2018 at the research farm of Shahroud University of Technology. , Located in the city of Bastam. Experimental treatments included: irrigation as main factor in three levels (irrigation every seven days, irrigation every 10 days and irrigation every 14 days) and priming treatments as sub factor in five levels (no priming (control) ), Hydropriming, gibberellic acid, salicylic acid and plasma. In this study, native seeds of Bastam region were used. The traits evaluated included yield and yield components, physiological and enzymatic properties. The results showed that increasing irrigation interval from seven days to 10 and 14 days, affected plant height, yield and yield components and decreased these traits. In addition, physiological and biochemical properties were also affected by these conditions, such that increased irrigation caused significantly increased proline, protein, flavonoid, malondialdehyde and enzymes levels. On the other hand, this stress decreased traits such as sodium, potassium, anthocyanin, relative leaf water content, plasma membrane stability, chlorophyll content and carotenoid content. Different priming treatments also had positive and significant effects on cowpea under different moisture conditions, so that priming increased the traits such as yield and yield components, sodium grain, potassium content, proline content, anthocyanin content, relative leaf water content. , Chlorophyll, carotenoid and enzyme levels. It also had a significant effect on flavonoid and malondialdehyde traits and decreased these traits. The results of this study showed that different priming treatments affected the characteristics of cowpea plant and the effects of moisture stress in this plant were reduced and moderated by priming.