Abstarct: Takht-e-Soleyman region is located in the southeast of West Azerbaijan province. The presence of karst limestones and the relatively high average annual rainfall in the region has led to the formation of karst springs such as Takht-e-Soleyman, Chartagh, Alasqal and Chopli Kani Shafa in the region. The main purpose of this research was to study the karst hydrogeological of Takht-e-Soleyman spring using geological, hydrogeological, hydrochemical and isotopic methods. The pH, EC, main ion concentrations, isotopic values of the springs and the rainfall and also flow rates of the springs has been measured. The equation of δ2H = 7.9δ18O + 19.6 was obtained for the isotopic meteoric water line of the Takht-e-Soleyman region, which has lower slope and intercept than the Global and Mediterranean water lines due to secondary evaporation. The relationship between altitude and the amount of oxygen 18 in this region is estimated as Elevation (m) = -223.5 δ18O + 40.2. The flow regime in the all springs is mostly diffuse flow. Also, the results of recession curve showed that Takht-e-Soleyman spring with two different recessions, mainly recharge through snowmelt to a karstic aquifer. The results of isotopic study showed that the spring water originates from atmospheric precipitation. The predominant water type of the springs is HCO3-Ca-Mg. All springs are saturated to super saturated with respect to calcite and dolomite, but under saturated with respect to gypsum and halite. The average annual recharge for Takht-e Soleiman, Chopli Kani Shafa and Alasqal catchments was 44%, 41% and 39%, respectively. Takht-e Soleyman catchment area was determined using the results obtained and the inquiry of various karst features.