Abstarct: The Quchan-Esfarayen magmatic belt is located in the in NE of Iran and north of Sabzevar structural sub-zone and Sabzevar ophiolitic belt (Binaloud zone, Eastern Alborz), where a thick sequence of Jurassic to Quaternary volcanic and volcanosedimentary rocks crop out. This sequence was intruded by numerous sub volcanic domes, dikes, with compositions ranging from andesite, trachyandesite to rhyolite. Various enclaves of different composition, size and shape have been found in these domes. These enclaves are evidence of magma mixing and crustal contamination. Geochemically, the studied rocks exhibit a calc-alkaline affinity, and they are enriched in LREE and LILE and depleted in HREE and HSFE. Other geochemical characteristics, such as SiO2 varying between 59-75 wt%, Na2O >3wt%, Al2O3 >15 wt%, Yb <1.8 ppm, Y <18 ppm and K2O /Na2O ratio between 0.1 to 0.9 percentage makes it possible to classify these rocks as high-silica adakites. Also, depletion of Nb and Ti, and a high enrichment in Rb, Ba, K and Th, implies crustal contamination of the adakitic domes. Petrographical and geochemical data indicate that the magma forming high-silica adakites originated from partial melting of the subducted and detached oceanic slab of Neo-Tethys (Sabzevar branch) in pressure-temperature conditions of amphibolite / eclogite facies. U-Pb zircon dating and K-Ar dating method on different rock groups yielded ages of 2.33±0.12 Ma to 17.81±0.15 Ma, which is consistent with early Miocene to late Pliocene. The ratio of 87 Sr/86 Sr (0.703903- 0.705627) and initial 143 Nd/144 Nd ratio of (0.512581-0.512803) suggest that these rocks originated from partial melting of the detached oceanic slab (Sabzevar branch). The investigated rocks are mainly composed of plagioclase, amphibole and pyroxene. Mineral chemical analysis reveals that plagioclase composition varies from oligoclase to andesine, clinopyroxene are mainly augite and amphibole varies from tschermakite to Mg-hornblende. Amphibole geothermobarometry suggests crystallization temperatures of 860–943ºC, at 1.70–4.08 Kb. Clinopyroxene crystallized at temperatures of 1150–1175ºC, at 3.80-5.90 Kb, indicating crystallization at crustal depths of maximum 20 km for the studied subvolcanic rocks in the Quchan-Esfarayen magmatic belt.