Abstarct: Irankuh Pb-Zn mine is located as one of the largest Pb-Zn mines in Iran has a great potential to become a source for contamination of surrounding soils through extraction and processing of ores. To evaluate the bioavailability of heavy mextals in soils around this mine and processing tailings dams, 31 soil samples, and 7 samples of plant (Ocimum basilicum) of agricultural land were collected and physicochemical parameters along with the concentration of heavy mextals were measured. According to the results obtained, most samples are Sandy loam and sandy clay loam in texture. Average pH, OM, CEC and CaCO3 were found as 7.82, 1.76 %, 10.76 meq/100 gr and 43.92%, respectively. Spatial variability analysis of mextal concentrations showed that concentrations of Zn, Pb and Cd are elevated near Irankuh mine and processing tailings dams. The correlation coefficient showed there is high correlation between these mextals and clay size fraction of soil samples. Also Enrichment factor and Geo-accumulation indexes hints to considerable soil pollution by Zn, Pb and Cd. Single extraction (DTPA) results revealed that bioavailability of the mextals in the soil depends on calcium carbonate percent in soils. However, cadmium has a more proportion of bioavailability (4 % to 60 %) as compared to the mextals Zn (1 % to 22 %) and Pb (1 % to 18 %). Concentration of mextals in plants varies as stem > leaf > root and in different parts of the plant as Zn > Pb > Cd. Concentrations of Pb and Cd in edible portions of the plant are significantly higher that their permissible concentrations in vegetables. Calculation of transfer factor for different mextals also showed that Cd has high availability where sea Zn and Pb have moderate availability to transfer from soil to plant. baxsed on the obtaiend results, there is the risk in terms of daily intake of vegetables with high contents of heavy mextals for consumers around the tailings dams.