Abstarct: Lead is one of most toxic pollutants in the environments. Lead mainly introduces into the water resources through industrial wastewater. The presence of lead in water resources is a serious environmental problem; therefore removal of lead from industrial wastewaters is very important. Among the various proposed methods for removal of toxic elements from the wastewaters; adsorption method has been vastly considered due to its high performance and economic benefits. In this study, the potential of red mud and coal fly ash and their different mixtures, as adsorbents for removal of lead from the experimental solutions was investigated. These materials were neutralized using seawater until a pH within the range 7.5 to 8 is achieved. The highest removal percentage of lead (99.7%) was observed for seawaterneutralized red mud. physicochemical properties of the seawater- neutralized red mud were studied by using instrumental technique (XRF, XRD, FTIR and SEM/EDX). The results showed the presence of Fe, Si and Al oxides and hydroxyl groups in the selected adsorbent which have a significant role in mextals adsorption from the industrial wastewaters. In the batch adsorption study, the role of pH, adsorbent dose, contact time, initial lead concentration, solution ionic strength and presence of other cations on pb removal was investigated. Maximum removal was achieved at pH= 5, the time equilibrium time of 30 min and the adsorbent dose of 0.5g. The experimental data fitted well with a Langmuir adsorption isotherm and the adsorption capacity was 49.5 mg/g. The adsorption kinetic studies indicated that the adsorption process was best described by pseudo-second-order kinetics. The effects of competitive ions is shown that Ca2+, Cu2+, Cd2+, Mg2+, K+ and Na+ have little effect on the removal percentage of lead. The effect of ionic strength on lead adsorption by seawater- neutralized red mud showed that lead may be adsorbed by strong binding chemical bonds via inner-sphere complexes. Quality assessment of obtained solution from adsorption experiment indicates the safety of the adsorption method for the environmental. A TCLP leaching test also reveals that the used adsorbent is not toxic and can be disposal as a non-hazardous waste. The obtained results showed that seawater- neutralized red mud is applicable for pb removal from real wastewaters.