QD262 : Using magnetized water as a promoting medium for synthesis of pyran derivatives
Thesis > Central Library of Shahrood University > Chemistry > MSc > 2016
Authors:
Abstarct: Tetrahydrobenzo[b]pyrans have several biological properties. So, providing a new methodology and synthesis of new derivatives are of interest. In this project, two methods were used for the synthesis of these compounds. Method 1: firstly [SiO2-Caff]HSO4 as a novel heterogeneouse catalyst was prepared; Then, the synthesis of 2-amino-4H-tetrahydrobenzo[b]pyran was catalyzed by [SiO2-Caff]HSO4 at 100oC under solvent-free conditions. Method 2: Three component reaction of 1,3-dicarbonyl compounds with aldehydes and malononitrile in magnetized water at room temperature afforded 2-amino-4H-tetrahydrobenzo[b]pyran.
The advantages of this two methods consist of using water as a green solvent, high yield, short reaction time and recycablity of the catalyst.
Keywords:
#Tetrahydrobenzo[b]pyran #three component reaction #magnetized water #heterogeneouse catalyst #solvent free conditions Link
Keeping place: Central Library of Shahrood University
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Keeping place: Central Library of Shahrood University
Visitor: