Abstarct: In recent years it has been proved that electro-synthesis is an efficient reagent-free method for selective synthesis of biological and pharmaceutical compounds. On the other hand, Michael addition reaction, as one of the effective organic reactions, has been shown its importance during last years. Herein, following on the previous works on electrochemical generation of quinones in the presence of various nucleophiles, we report the electrochemically oxidation of catechol, 3-Methoxycatechol and 3-Methylcatechol in the presence of 4-propyl-2-thiouracil as a possible nucleophile.the catechol derivatives react with through Michael addition reaction by applying potential at buaffer (0/15 M, PH=6/8), water /DMF (90/10) solution and using cyclic voltammetry and controlled-potential coulometry. The results indicate that catechol and its derivatives react with 4-propyl-2-thiouracil under ECEC mechanism and give products. The product has been characterized by IR, 13CNMR, 1HNMR and TLC and melting point.