Abstarct: Objective: The aim of this study was to investigate the effect of 8 weeks of compound exercises with Omega-3 and l-carnitine supplementation intake on serum levels of Visfatin in type II Diabetic Women. Methods: this quasi-experimental study included a pre-test and post-test. Participants of the study were type II diabetic women with an average age of (52.7 ± 1.6 years) and (body mass index 29.82 ± 4.35 kg/m²) who were randomly divided into 6 groups of 10 individuals: 1. exercise 2. exe + omega-3, 3. exercise + L carnitine, 4. exercise + omega 3 + L- carnitine, 5. L-carnitine + omega-3 and 6. control group. Omega-3 supplementation groups was daily consumed 2000 mg of omega-3 and L-carnitine group 500 mg L-carnitine. Training included 3 times a week and each session consisted 30 minute of aerobic exercise with 60-70% of maximum heart rate and 30-40 minute of circular resistance training with 60% 1RM, With 10 repetitions for 3 sets in motion consecutive 30-second rest between each station and remnants or around 120 seconds of rest between each set was done. Resistance training involves 10 moves in a circular station was planned. Dependent t-test to evaluate differences within a group, analysis of covariance to assess the difference between the group and the Bonferroni post hoc test to identify the groups that make a difference in the analysis of covariance had given a significant level of p≤0.05 was used. Results: Results Comparison within groups showed that visfatin levels in groups of 3 (p=0.04), 4 (p=0.009) and 5 (p=0.01) after the intervention was decreased and, The levels of Fast glucose in groups 1 (p=0.005), 2 (p=0.003), 4 (p=0.004) and 5 (p=0.04) after the intervention had a significant reduction. insulin resistance in groups 2 (p=0.04) and 5 (p=0.01) after the intervention showed a significant reduction. compared between groups were significant increases in HDL caused by a group of 4 (p=0.001) and 5 (p=0.002). LDL decreased significantly in both groups of 4 (p=0.003) and 5 (p=0.05) compared within groups. In compared between groups, groups of 2 (p=0.02), 4 (p=0.04) and 5 (p=0.001) on a significant reduction of serum TG the control group had created. compared within groups a significant decrease in BMI index was observed after treatment in group 4 (p=0.001) and 5 (p=0.005). In compared between groups test between the Group 3 (p=0.02) and 4 (p=0.001) decreased significantly in the index, WHR showed. Reduced serum levels of HbA1C in groups 1 (p=0.05), 2 (p=0.04), 4 (p=0.003) and 5 (p=0.001) after the intervention was observed. VO2max also in group 4 (p=0.05) was significantly increased after intervention. Conclusion: The results of this study, it seems, compouned exercises and Omega-3 and l-carnitine together supplementation intake appropriate stimulus to reduce visfatin levels and reduce risk factors in type 2 diabetic women.