Abstarct: In this research, for the first time from garlic and pomegranate extracts were used as a reducing and stabilizing agent for the preparation of copper nanoparticles from copper sulfate. These copper nanoparticles were characterized by XRD, UV-Visible and FT-IR spectrometry, SEM, TEM, TGA and EDX. A absorbance observed in (793 nm) in UV-Vis spectra of solution is due to surface plasma resonance of Cu NPs. The results of the XRD diffraction pattern showed that the average size of copper particles of garlic and pomegranate peel extracts are 65 and 92 nm, respectively. The morphology of synthesized nanoparticles by scanning electron microscopy shows that spherical copper nanoparticles are irregular. Transmission electron microscope estimates the average particle size of the garlic extract of about 70 nm. Finally, synthetic copper nanoparticles were used as nanocatalysts in the process of methylene blue resuscitation by NaBH4 and the effect of different factors (concentration of paint, nanoparticles and pH) on this process was studied. Took. The results of the catalytic process analysis showed that in the same amounts of nanoparticles and NaBH4, increasing the color-seed concentration, more time is needed for the reduction process. If, at the same concentration of methylene blue, the increase in the amount of nanoparticles accelerates the reaction rate. The results of pH effect on catalytic action of copper nanoparticles showed that in certain amounts of nanoparticles, the rate of methylene blue reduction in the acid environment was more than the neutral medium and more than the alkaline medium.