Abstarct: In this experimental research work we have studied morphological, structural, electrical, optical and photoconductivity properties of nickel oxide nano-grains thin laxyers of pure and doped grown by spray pyrolysis method. For physical characterization of samples we have used field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), UV-Vis.-NIR spectroscopy, current-voltage measurement and Seebeck effect experiment. In fabrication of NiO laxyers produced by NiCl2+6H2O powder various parameters were investigated. These parameters are including: the precursor volume, the doping effect with Li, Cu and Co atoms, i.e. NiO:Li, NiO:Cu and NiO:Co. The FESEM images of the samples show a fairly regular formation of nano particles on the surface of the laxyers. The XRD patterns show all films have a polycrystalline cubic structure mainly oriented along (111) direction. The transmission spectra of the samples indicate that all samples are transparent in the visible range that varies with various growth conditions. The data analysis show the band gap of this material changes between 3.2-3.9 eV. The I-V characteristics of the samples at room temperature revealed that the sheet resistances of the grown laxyers are relatively high (about 106 Ω). Finally the Seebeck effect proves that all samples have p-type conductivity. Due to the wide band gap in this material, all the samples were studied for the photoconductivity effect. We found this material is a good candidate for UV light detection.