Abstarct: Background and Objectives: Observations have shown that visceral adipose tissue produces melanoma similar to cellular aging and activates cytokines and chemokines of the P53 and IL-6 and P16 genes. To date, there are no studies on the effects of exercise on the exxpression of aging-related genes in visceral adipose tissue. Therefore, the aim of the present study was to compare the differences between endurance training and resistance training on the exxpression of aging-dependent genes in visceral adipose tissue of young mice. Materials and Methods: In the present study, 15 male Wistar rats ate the available high-fat diet for nine weeks. After reaching the stage of obesity, rats were randomly divided into three groups of 5 including control group, endurance group and resistance group. Subsequently, the high-fat diet of the animals was changed to the standard diet. Rats trained five sessions per week for 8 weeks. In each resistance training session, a resistance ladder with a height of one meter and a slope of 85 degrees and bars with a distance of 2 cm were used in the resistance training. Each training session consisted of 3 sets with 5 repetitions. The rest interval between each set was 2 minutes and between each repetition was one minute. The rats at the beginning (interval between repetitions one minute) and at the end (interval between repetitions 3 minutes) each session performed a 5 repetition set without weights with the aim of warming up and cooling down. The recorded VO2max speed was the speed at which VO2 reached the plateau; Which was obtained by measuring the concentration of lactate through a lactometer and if it was more than six mmol / l, it meant reaching a speed of VO2max. The rats then exercised five sessions per week for eight weeks according to an exercise program baxsed on a percentage of VO2max baxsed on research by Lamitsu et al. (2005). At the same time, the control group did not have any training. After 5 to 10 minutes of warm-up with 50 to 60% VO2max intensity, the endurance training group practiced continuously for 50 minutes with 65 to 70% VO2max intensity, and at the end, they cooled with 50-60% VO2max intensity for 5 minutes. At the end of the training period, all the studied animals were killed and operated on using the appropriate method of facilitation. exxpression levels of 53P, 16P and 6IL-genes were measured by Real time RT-PCR. Data were analyzed by SPSS software using Shapiro-Wilk test (to check the normality of data) and one-way analysis of variance (to test hypotheses). Results: There was a significant difference between the exxpression of 53P and 6 IL- and P16 genes compared to the reference gene in the three groups of subjects (p <0.05). On the other hand, between the exxpression of P53 and IL-6 and P16 relative to the reference gene, however, the decrease in exxpression of the results of this study showed that there was no significant difference in the exxpression of these genes compared to the reference gene between the endurance and resistance groups. Conclusion: In general, the results of the present study showed that 8 weeks o : endurance and resistance training can significantly reduce the exxpression of P53 and IL-6 and P16 genes compared to the reference gene, compared with the control group. These changes were significantly different between the two groups of resistance and endurance and endurance training was more effective